TZPSS Articles | Health | PARKINSON'S DISEASE

Parkinson's Disease

Parkinson's disease is a chronic, progressive
neurodegenerative condition caused by the destruction of the
brain cells that produce dopamine. As the level of this chemical
declines, messages from the brain telling the body how and
when to move are delivered more slowly, leaving a person
incapable of initiating and controlling movements in a normal
way. Parkinson's is a relentless disease with limited treatment
options. This is a welcome development for the more than
50,000 Americans who are each year diagnosed with
Parkinson's disease. Currently, Levodopa is a standard
treatment for Parkinson's disease. The safety and
effectiveness of Azilect was demonstrated in three 18- to
26-week controlled clinical trials.

Azilect approved for Parkison's Disease

The Food and Drug Administration approved Azilect
(rasagiline), a new molecular entity, for use as an initial single
drug therapy in early Parkinson's disease, and as an addition
to levodopa in more advanced patients. The drug is a
monoamine oxidase type--B (MAO-B) inhibitor that blocks the
breakdown of dopamine, a chemical that sends information to
the parts of the brain that control movement and coordination.

Azilect may be associated with hypertensive crisis if patients
also consume tyramine-rich foods, beverages (such as cheese
and red wine) or dietary supplements or amines contained in
many cough/cold medications. Therefore, patients will need to
avoid these sources of tyramine and amines when taking
Azilect. As with most other medications for Parkinson's,
Azilect has the potential to cause involuntary movements
(dyskinesias), hallucinations and lowered blood pressure.
These side effects are described in the product labeling.

FDA Approves New Treatment for Parkinson's Disease FDA News May 17, 2006

This article can not be replaced for medical advice. If you have question, you should consult with your doctor
immediately. ALL RIGHT RESERVED 2007

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